High-Fat Diet May Lead to Depression

New studies have linked depression & other mental problems to high-fat diets. This type of diet can also lead to brain inflammation & affect human behavior as well. As it is, a diet high in fat was tied to physical health problems including increased risk of heart attacks & strokes. Gut micro-biome, comprising a complete mix of bacteria in the human digestive system eventually get altered by consuming diet rich in fat. A typical human body contains almost trillions of such microorganisms.


High-Fat Diet Research on Mice
Mice fed on a normal diet were implanted with bacteria from rodents fed with large doses of high-fat foods. Monitored over time, the behavior & cognition of these animals were measured against a control group who had received microbes from mice on a normal diet. Louisiana State University researchers were trying to find out whether gut bacteria can alter behavioral patterns even among animal who do not exhibit obesity concerns.

High-Fat Diet Study
It was found that mice who had received implanted bacteria from rodents on high-fat diet exhibited anxiety, repetitive behavior & memory impairment. Signs of increased permeability & inflammation were also recorded in their intestines. Brain inflammation was also observed in mice with implanted bacteria which might have been responsible for behavioral changes seen in them.

High-Fat Diet Suggestions

This report suggests that high-fat diet impair brain health in part, by disrupting the symbiotic relationship existing between humans & microorganisms, occupying our gastrointestinal tracts. This study goes on to suggest that such behavioral changes also occur in animals who are not obese. Detailed mechanism caused by high-fat diet is still unknown & future research can establish how bacteria in gut are able to alter behavior.

Backed by Previous Research
Prior research had established a correlation between gut bacteria & some psychological conditions. This new study enjoins supportive evidence to earlier findings. Microbiome alterations are also previously tied to body-ability in fighting illness & heal injuries. Depression & obesity are known to be largely influenced by genetics. People in depression often tend to eat high-fat diets in order to feel better, while attached social stigmas invariably increase feelings of depression.

Relation Between High-Fat Diet & Depression
Another recent study found obese individuals to have a 20% elevated risk of getting into depression. Moreover, college-educated obese subjects risk of depression rises to almost as high as 44 percent. This study establishes an additional tie-up between these two conditions. This analysis of role of gut bacteria & high-fat diet on mental health is profiled in Biological Psychiatry journal.



 

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